Shugo Honda Selected Research

O-(glucuronic acid 2- sulfate)- (1- - 4)- O- (2,5)- anhydromannitol 6-sulfate

1/2020	Optimization and biological evaluation of imidazopyridine derivatives as a novel scaffold for γ-secretase modulators with oral efficacy against cognitive deficits in Alzheimer's disease model mice.
1/2020	Discovery of N-ethylpyridine-2-carboxamide derivatives as a novel scaffold for orally active γ-secretase modulators.
1/2018	Discovery of novel scaffolds for γ-secretase modulators without an arylimidazole moiety.

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Shugo Honda Research Topics

Disease

3	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 01/2018
1	Chronic Pain 12/2014
1	Neuralgia (Stump Neuralgia) 12/2014

Drug/Important Bio-Agent (IBA)

3	Gamma Secretase Inhibitors and ModulatorsIBA 01/2020 - 01/2018
3	O-(glucuronic acid 2- sulfate)- (1- - 4)- O- (2,5)- anhydromannitol 6-sulfateIBA 01/2020 - 01/2018
1	imidazopyridineIBA 01/2020
1	Biological ProductsIBA 01/2020
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2020
1	Amyloid (Amyloid Fibrils)IBA 01/2018
1	N-Type Calcium Channels (N-Type Calcium Channel)IBA 12/2014
1	ziconotide (Prialt)FDA Link 12/2014

Therapy/Procedure

1	Ligation 12/2014